Plenary III: Foundation and Future in Neuromodulation Science
President-elect
Saturday, January 24, 2026
8:50 AM - 8:55 AM PST
Location: Octavius Ballroom 4
Session
Description: As neuromodulation enters a new era of innovation, it becomes increasingly vital to revisit its scientific foundations while exploring how we define, measure, and validate clinical success. Foundation and Future in Neuromodulation Science will bring together three renowned thought leaders whose landmark work has shaped how we understand the mechanisms and evaluate the outcomes of neuromodulation. This session will begin with a presentation by Dr. Apkar Vania Apkarian, a pioneering neuroscientist whose use of advanced neuroimaging has provided unprecedented insights into the mechanisms of pain and neuromodulation. His work using functional MRI to characterize brain circuitry alterations in chronic pain has laid the groundwork for mechanism-targeted therapies. Following this presentation, Dr. Sean Mackey, who is an expert in clinical outcomes research and pain measurement, will present on how we quantify the treatment effects of neuromodulation and pain interventions, exploring the interplay between objective data and the lived patient experience.
Following these presentations, a moderated panel discussion will provide an opportunity for interactive dialogue with the speakers, exploring implications for trial design, biomarker development, and translational science.
This plenary will conclude with the introduction of the NANS President and the delivery of the Presidential Address and Lifetime Achievement Award, spotlighting both the current and future landscape and legacy of leadership in neuromodulation.